Croatian mezzo-soprano Sofia Ameli was born in Sisak, where she started her education in music and performing arts. She graduated opera singing at the Academy of Music, Zagreb University, in the class of Prof. Nada Puttar-Gold. For extraordinary achievements and artistic performances during her study, she was given award by the University of Zagreb. Continued her post-graduate study at the University of Music and Performing Arts in Vienna, Austria, in the class of Prof. Leopold Spitzer. She also worked with distinguished pedagogue Stojan Stojanov Gancev.

Since finishing her studies, she is engaged as a soloist in the Opera of Croatian National Theatre in Zagreb. At the same time, she performs as a guest singer in other Opera Houses and Concert Halls in Croatia, as well as in Austria, Bosnia and Herzegovina, Italy, Macedonia, Montenegro, Serbia and Slovenia. She has performed a wide range of opera roles in forty different opera productions, among which are the roles of Azucena (Il Trovatore), Carmen (Carmen), Eboli (Don Calos), Fenena (Nabucco), Rosina (Il Barbiere di Siviglia), Santuzza (Cavalleria Rusticana), Ulrica (Un Ballo in Maschera), Zia Principessa (Suor Angelica) etc. Along with the standard opera repertoire, she is known as a performer of contemporary music. She has performed different leading roles in contemporary operas, such as Greta (The Metamorphosis), Marianne (Stories from the Vienna Forest), Girl (Talk to me about Augusta), Mrs. Steel (Penguins).

She recorded various pieces of contemporary music and different projects for Croatian Radio and Television, RTV Macedonia, RTV Montenegro, Radio Television of Serbia and Swiss television. Her artistic activities include concerts with Zagreb Philharmonic Orchestra, Croatian Radio and Television Symphony Orchestra, Croatian Chamber Orchestra, Orchestra of the Ljubljana Opera, Cantus Ensemble, String Orchestra Dusan Skovran, Montenegrin Symphony Orchestra etc. She has participated in opera festivals and festivals of contemporary music: Music Biennale Zagreb, Gostic Days, Days of Croatian Music, Grosseto Festival, May Opera Evenings in Skopje, Kampnagel in Hamburg and others.

In the year 2005 she was awarded for life achievements with the Gold Medal of „Mare Nostrum Croaticum“ as the youngest opera singer who won this award ever.